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Compounds

Cat No. Product Name Synonyms Targets
T4820 Maleimide 2,5-Pyrroledione Others
Maleimide (2,5-Pyrroledione) (2,5-Pyrroledone) is a new nanoparticle surface functional group which favors easy conjugation with cell penetration peptides. The conjugation is enabled via click chemistry to preserve its b...
T18479 NH-bis(C1-Boc) Others
NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC).
T21408 DM1-SMe DM1-SSMe Microtubule Associated
DM1-SMe (DM1-SSMe) is a potent inhibitor of maytansinoid microtubular. DM1-SMe is about 3 to 10-fold more potent than the parent drug Maytansine, with IC50s of 0.003 to 0.01 nM for DM1-SMe in a panel of human tumor cell ...
T4289 Mc-​Val-​Ala-​PAB Mc-Val-Ala-PAB Others , AChR
Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).
T14061 EMCS 6-Maleimidohexanoic acid N-hydroxysuccinimide ester Others
EMCS (6-Maleimidohexanoic acid N-hydroxysuccinimide ester) is a heterobifunctional crosslinking agent, which is a compound for the preparation of hapten conjugate and enzyme immune conjugate, and an effective protective ...
T76769 Indusatumab Guanylate cyclase
Indusatumab (5F9 Monoclonal antibody) is an anti-human GUCY2C (Guanylate cyclase 2C) monoclonal antibody that can be used to synthesize antibody-drug conjugate.
T16899 SMCC-DM1 DM1-SMCC Others
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
T1910 Ansamitocin P 3' Maytansinol butyrate,Ansamitocin P-3,Antibiotic C 15003P3' Microtubule Associated
Ansamitocin P 3' (Maytansinol butyrate) is an antibody-drug conjugate cytotoxin with antitumor activity.
T77406 Lorvotuzumab Others
Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1). Lorvotuzumab can be used to synthesize antibody-drug conjugate (Lorvotuzumab mertansine).
T15141 DM4 Ravtansine Others , Microtubule Associated
DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.
T16031 McMMAF Maleimidocaproyl monomethylauristatin F Microtubule Associated
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other prote...
T18529 PDEC-NB 4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate Others
PDEC-NB (4-Nitrophenyl 2-(Pyridin-2-Yldisulfanyl)Ethyl Carbonate) is a disulfide cleavable linker. PDEC-NB can be used for the antibody-drug conjugate (ADC).
T5149 MC-Val-Cit-PAB Others , AChR
MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.
T18870 Vc-MMAD Others
Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs t...
T17731L CL2A-SN-38 DCA 1279680-68-0(free base) Others
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibito...
T15176 DSS Crosslinker Others
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters a...
T77909 Mirzotamab
Mirzotamab, an IgG1κ antibody, targets CD276/B7-H3 and conjugates with Clezutoclax, a BCL-2 inhibitor, to create Mirzotamab clezutoclax. This antibody-drug conjugate (ADC), identified as ABBV-155, is currently under inve...
T4286 Fmoc-Val-Ala-PAB-OH Fmoc-Val-Ala-PAB Others , AChR
Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-paclitaxel conjugates...
FL0195 N-Boc-4-hydroxy-L-proline methyl ester
N-Boc-cis-4-hydroxy-L-proline methyl ester serves as a non-cleavable linker in antibody-drug conjugate (ADC) synthesis and functions as an alkyl chain-based PROTAC linker for PROTAC construction[2].
T9227 Val-Ala-PAB Others
Val-Ala-PAB is a building block in the synthesis of Tesirine (a.k.a. SG3249), a clinical antibody-drug conjugate pyrrolobenzodiazepine dimer payload. Reagent in the preparation of pyrrolobenzodiazepine dimers and their a...
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